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采用塑料包埋薄切片技术对52例白血病骨髓活组织进行病理检查结果显示:32例急性白血病中24例伴有不同程度纤维细胞增加或纤维化,其程度越重预后越差。20例慢性粒细胞白血病全部伴有纤维细胞增加或不同程度纤维化,程度越严重脾脏越大。同时本文对化疗前后基质损伤程度与预后关系等问题进行了讨论。
Pathological examination of 52 cases of leukemia bone marrow biopsy using plastic-embedded thin section technique showed that in 32 cases of acute leukemia, 24 cases were accompanied by varying degrees of fibrocyte increase or fibrosis, the worse the prognosis was. 20 cases of chronic myeloid leukemia all accompanied by increased fibrosis or fibrosis, the more serious the greater the spleen. At the same time, the paper discusses the relationship between the degree of matrix damage and prognosis before and after chemotherapy.