目的　评价OhmedaExcel 2 10麻醉机 +790 0呼吸机紧闭循环通气用于婴儿麻醉的可行性。方法　选择 10kg以下婴儿唇裂或腭裂手术病例 30例。以同组病例前后比较紧闭循环通气与Jackson Rees婴儿回路通气的各项呼吸动力学指标。以呼吸频率 (RR) =2 2次 /min ,I:E =1:1 5及PETCO2 =40mmHg为控制值 ,相应调节潮气量。观测紧闭循环通气与Jackson Rees婴儿回路通气的潮气量 (VT) ,气道峰压 (Ppeak) ,呼气末压力 (PEEP) ,呼吸总顺应性 (CT) ,第一秒呼气比率(FEV1 0 % ) ,吸入气中二氧化碳浓度 (FiCO2 ) ,脉搏氧饱和度 (SpO2 )等指标。结果　与Jackson Rees婴儿回路通气相比 ,紧闭循环通气的PEEP显著升高 ,而FiCO2 显著降低 (P <0 0 1)。两组间FEV1 0 % 、Ppeak、VT、CT、SpO2 的差异无显著性 (P >0 0 5 )。结论　婴儿麻醉应用OhmedaExcel 2 10麻醉机 +790 0呼吸机紧闭循环通气是可行的。 Objective To evaluate the feasibility of OhmedaExcel 2 10 anesthesia machine +790 0 ventilator closed loop ventilation for infant anesthesia. Methods 30 cases of cleft lip or cleft palate in 10kg or less infants were selected. Comparisons of respiratory dynamics between closed loop ventilation and Jackson Rees infants’ loop ventilation were performed before and after the same group of patients. The respiratory rate (RR) = 2 2 times / min, I: E = 1: 1 5 and PETCO2 = 40mmHg as the control value, adjust the tidal volume accordingly. Tight closed circulatory ventilation was compared with Jackson Rees tidal volume (VT), Ppeak, end-expiratory pressure (PEEP), total respiratory compliance (CT), first-second exhalation rate 0%), carbon dioxide concentration in inhaled gas (FiCO2), pulse oxygen saturation (SpO2) and other indicators. Results Compared with Jackson Rees infants, PEEP significantly increased while FiCO2 decreased significantly (P <0.01). There were no significant differences in FEV1 0%, Ppeak, VT, CT, SpO2 between the two groups (P> 0.05). Conclusion The anesthesia in babies OhmedaExcel 2 10 anesthesia machine +790 0 ventilator closed circulation ventilation is feasible.