双轻链病为单克隆γ_1病的极为罕见的病种,我国未见报告,国外也只见过2例报告。最近我们发现1例:孟某,男,52岁,济南市历下人民医院住院病人。患者因乏力、疲劳、纳差、浮肿、腰痛、尿蛋白已3年,肩胛区、季肋部及腰椎疼痛1年多,加重1个月住院。体检:慢性病容,一般情况甚差,贫血貌及脸部浮肿,肝在右肋下两指,全身多处骨骼有明显触痛,肩胛部及腰椎处可摸到1×2cm大小、质靭、固定、表面光滑之包块。Hb3.2克％, Double light chain disease is a very rare disease of monoclonal γ_1 disease, no report has been reported in our country and only 2 cases have been reported abroad. Recently, we found a case: Mengmou, male, 52 years old, Jinan City People’s Hospital under the calendar of patients. Patients due to fatigue, fatigue, anorexia, edema, back pain, urinary protein has been 3 years, scapular area, quarter ribs and lumbar pain more than 1 year, increased 1 month hospitalization. Physical examination: Chronic disease, the general situation is very poor, anemia appearance and facial edema, the liver in the right rib two fingers, multiple body parts have obvious tenderness, scapular and lumbar Department can touch 1 × 2cm size, quality and toughness, Fixed, smooth surface of the block. Hb3.2 g%,