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Herpessimplexvirustype2(HSV2)是外阴疱疹及宫颈癌等多种疾病的病因之一。阿昔洛韦(acyclovir,ACV)治疗HSV2感染易产生耐药毒株;cidofovir肾毒性很大;HSV疫苗效果不佳。因此,研制抗病毒新药是相当重要
Herpessimplex virus type 2 (HSV 2) is one of the causes of various diseases such as vulvar herpes and cervical cancer. Acyclovir (ACV) treatment of HSV 2 infection is easy to produce drug resistant strains; cidofovir has a large nephrotoxicity; HSV vaccine is not effective. Therefore, it is very important to develop new antiviral drugs.