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作者采用ELISA方法检测了脐血、正常新生儿、新生儿败血症及败血症性休克患儿血清IL- 6水平。结果表明,正常情况下脐血及新生儿血清IL- 6水平极低,而细菌感染时IL- 6水平迅速升高,并与新生儿败血症感染的病情程度和预后存在联系。提示病程初期检测血清IL- 6可能对新生儿败血症的早期诊断和判断预后有一定的临床实用价值。
The authors used ELISA method to detect serum IL-6 levels in cord blood, normal newborns, neonatal sepsis and septic shock. The results showed that the levels of IL-6 in umbilical cord blood and neonates were very low in normal conditions, while the level of IL-6 in bacterial infections increased rapidly, which was related to the severity and prognosis of neonatal sepsis infection. It is suggested that the initial detection of serum IL-6 in course of disease may have clinical value in the early diagnosis and prognosis of neonatal sepsis.