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目的:研究高血压家族史对高血压病患病率的影响及遗传方式。方法:采用家系调查法对全区同一地方有、无高血压家族史的两两人群高血压患病率对比分析。结果:高血压病患病率,有高血压家族史>高血压家族史不详>无高血压家族史,三者互比差异极显著(P<0.001)。有高血压家族史高血压病发生RR347,AR1808,ARP1853%,高血压家族史与高血压病患病率呈正相关。父母均有高血压子女高血压病患病率高于父或母有高血压者(P<0.001)。结论:家族性高血压病可能为常染色体遗传性疾病。将有高血压家族史的人群应视为高血压病易患人群,应加强高血压病的一级预防。对有高血压家族史者或双亲均有高血压病的子女,建议优生咨询。
Objective: To study the influence of family history of hypertension on the prevalence of hypertension and its hereditary patterns. Methods: The prevalence rate of hypertension among two groups with and without family history of hypertension in the same place in the same district was analyzed by pedigree investigation method. Results: The prevalence of hypertension, familial history of hypertension, familial history of hypertension, family history of hypertension, were significantly different (P <0.001). Hypertension family history of hypertension RR3 47, AR18 08, ARP18 53%, family history of hypertension and hypertension prevalence was positively correlated. Hypertensive children with both parents have higher prevalence of hypertension than those with either parental hypertension (P <0.001). Conclusion: Familial hypertension may be autosomal genetic disease. People with a family history of hypertension should be considered as predisposed to hypertension, and primary prevention of hypertension should be strengthened. For those who have a family history of hypertension or both parents have hypertension, recommended eugenic counseling.