传统理论认为肿瘤形成是由于人体在多种因素影响下使某一部分细胞发生一系列基因突变而具有不受机体控制的无限增殖能力所导致,其中具有转移能力肿瘤称为恶性肿瘤。长久以来,人们一直认为肿瘤生长是所有肿瘤细胞共同作用结果。而Reya等[1]提出的“肿瘤干细胞学说”指出肿瘤生长和转移是由于其内部一部分具有干细胞特征的肿瘤细胞增殖和迁移所造成的结果,即在肿瘤组织中存在一种数量较少干细胞样癌细胞亚群,其同时具有癌细胞和干细胞特征,是肿 The traditional theory that the formation of tumors is due to a variety of factors under the influence of a certain number of cells in a series of gene mutations and have unlimited control of the proliferation of body caused by the ability of metastatic tumors known as malignant tumors. For a long time, people always think that tumor growth is the result of the action of all tumor cells. However, Reya et al. [1] suggested that “tumor stem cell theory” indicates that tumor growth and metastasis are the result of proliferation and migration of tumor cells characterized by stem cells within a part of them. That is, there is a small number in tumor tissues Stem cell-like cancer cell subsets, which have both cancer and stem cell features, are swollen