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目的 :探讨重组人生长激素(rhGH)应用于治疗烧伤患者的疗效。方法 :将60例烧伤患者随机分成观察组与对照组,各30例,两组均接受常规治疗,观察组加用rhGH治疗,对比两组的临床疗效。结果 :观察组的深Ⅱ度创面、植皮区及供皮区创面愈合时间、住院时间均较对照组显著缩短(P<0.05);治疗后观察组的Hb、IL-6及TNF-α均较治疗前及对照组显著降低(P<0.05),PT较治疗前及对照组显著提高(P<0.05)。结论:rhGH辅助治疗烧伤可控制炎症反应、促进血浆蛋白的合成及创面愈合,值得推广应用。
Objective: To investigate the effect of recombinant human growth hormone (rhGH) in the treatment of burn patients. Methods: Sixty patients with burn were randomly divided into observation group and control group, 30 cases in each group. Both groups received routine treatment. The observation group was treated with rhGH, and the clinical efficacy was compared between the two groups. Results: The wound healing time and hospital stay of deep second degree wounds, skin grafts and donor sites in observation group were significantly shorter than those in control group (P <0.05). The levels of Hb, IL-6 and TNF-α in observation group were significantly lower than those in control group Before treatment and control group was significantly lower (P <0.05), PT than before treatment and control group was significantly increased (P <0.05). Conclusion: rhGH adjuvant treatment of burn can control the inflammatory response, promote the synthesis of plasma protein and wound healing, which is worth popularizing and applying.