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SLE和普通可变的低γ球蛋白血症(CVH)均属B淋巴细胞机能障碍所致的一类疾病。SLE伴发CVH不常见,现报告1例。患者,女性,36岁。1967年10月诊为SLE,当时有体重减轻,全身性红斑,雷诺氏现象及对称性膝、踝、趾关节炎。WBC3950,ANA阳性,LE细胞(+),梅毒血清试验假阳性,肾功检查正常,γ球蛋白3.19g/dl。1968年5月狼疮恶化,服强的松,5～40mg/d。早期曾伴发急性腮腺炎,缺血性小腿溃疡,但无典型肾病。1969年6月,因SLE多次复发,
SLE and common variable low-gamma globulin (CVH) are a class of diseases caused by B lymphocyte dysfunction. SLE with CVH is not common, is reported in 1 case. Patient, female, 36 years old. October 1967 diagnosis of SLE, there was weight loss, systemic erythema, Raynaud’s phenomenon and symmetry knee, ankle, toe arthritis. WBC3950, ANA positive, LE cells (+), syphilis serum test false positive, normal renal function examination, gamma globulin 3.19g / dl. May 1968 lupus worsening, strong prednisone, 5 ~ 40mg / d. Early with acute parotitis, ischemic leg ulcers, but no typical nephropathy. June 1969, due to multiple recurrence of SLE,