论文部分内容阅读
本实验用胆固醇粉喂家兔，造成实验性高脂血症，活体观察球结膜微循环的形态、流态及血管周围状态等１５项指标，并用球结膜微循环综合定量评价方法计算了综合积分值。处死后取球结膜进行组织学检查。结果表明：高脂血症家兔球结膜微循环有明显改变，主要为微血管形态异常、血流减慢、红细胞聚集、白微栓、静脉壁上有白色斑块等改变。球结膜微循环综合积分值明显增加，高于实验前。球结膜组织学检查发现上皮层下有泡沫细胞、血管壁增厚、有空泡、静脉内有血栓。虹膜睫状体内除有多数泡沫细胞外，还有胆固醇的菱形结晶。上述改变表明，高脂血症兔球结膜微循环有明显改变。血液有高凝、高聚倾向。黑茶中的茶色素有抗凝、抑制血小板聚集、促进纤溶等作用，口服黑茶可改善高脂血症兔球结膜微循环障碍。
In this experiment, cholesterol was fed to rabbits, resulting in experimental hyperlipidemia. The morphological, flow and perivascular status of the conjunctiva microcirculation were observed in vivo. The integrated score of the conjunctival microcirculation comprehensive quantitative evaluation was calculated. value. After taking the ball conjunctiva for histological examination. The results showed that there were significant changes in the conjunctival microcirculation in rabbits with hyperlipidemia mainly including abnormal microvascular morphology, slow blood flow, aggregation of erythrocytes, white micro-emboli and white plaque on the vein wall. Bulb conjunctival microcirculation integrated score was significantly increased, higher than before the experiment. Bulbar conjunctival histological examination found that there are foam cells under the epithelium, thickening of the blood vessel wall, there is empty bubble, thrombosis in the vein. In addition to the majority of iris ciliary body cells in foam, there are diamond crystals of cholesterol. The above changes show that hyperlipemia rabbit conjunctiva microcirculation significantly changed. High blood coagulation, high poly tendency. Black tea pigment in the anticoagulant, inhibition of platelet aggregation, fibrinolysis and other effects, oral black tea can improve hyperlipemia rabbit conjunctiva microcirculation.