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目的:总结剖宫产围手术期预防性应用抗生素的方案和效果。方法:回顾性分析2010年11月至2012年10月在我院剖宫产分娩215例的临床资料,将围手术期预防性使用第一代头孢菌素24小时者为观察组(n=113),以同期术后使用同种抗生素72小时以上者为对照组(n=102),比较两组感染指标、住院时间及药物费用。结果:观察组的住院时间和药物费用均明显低于对照组,P<0.05;但两组术后体温、白细胞数、产褥病、伤口感染、盆腔炎均无显著性差异(P>0.05)。结论:在无感染高危因素的剖宫产围手术期24小时内预防性使用抗生素基本可行。
Objective: To summarize the scheme and effect of prophylactic antibiotics in perioperative period of cesarean section. Methods: The clinical data of 215 cases delivered by cesarean section in our hospital from November 2010 to October 2012 were retrospectively analyzed. The patients who took prophylactic use of first-generation cephalosporins for 24 hours perioperatively as observation group (n = 113 ), With the same period after the same antibiotics for more than 72 hours as the control group (n = 102), the two groups were compared infection index, hospitalization time and drug costs. Results: The hospitalization time and drug cost in the observation group were significantly lower than those in the control group (P <0.05). However, there was no significant difference in body temperature, white blood cell count, puerperal disease, wound infection and pelvic inflammatory disease between the two groups (P> 0.05) . Conclusion: It is feasible to use prophylactic antibiotics within 24 hours of cesarean section without risk of infection in perioperative period.