细菌、酵母、植物、朴状病毒和哺乳动物细胞表达系统都可用于抗体生产，各有利弊。细菌由于缺乏糖基化能力，不能催化IgFc上糖基转移；此外，它不能装配完整的抗体和不利于抗体分子形成适当的链内和链间二硫键。酵母可以表达完全抗体，但是由于它们具有高甘露糖、多分技寡聚糖 Bacteria, yeasts, plants, innate viruses, and mammalian cell expression systems are all useful for antibody production, each with its own advantages and disadvantages. Bacteria, due to their lack of glycosylation capacity, can not catalyze glycosyltransferases on IgFc; in addition, they can not assemble intact antibodies and detrimentally form antibody molecules to form appropriate interchain and interchain disulfide bonds. Yeast can express complete antibodies, but because of their high mannose, polysaccharides