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目的探讨氟喹诺酮类抗菌药物培氟沙星引起过敏性休克的特点与规律,为临床合理使用培氟沙星提供参考。方法:通过国内有关医药数据库检索关于培氟沙星致过敏性休克的病例报告,下载原始病例资料手工统计分析。结果培氟沙星致过敏性休克17例,15例为静脉注射引起,2例口服给药引起;其中2例死亡。结论培氟沙星引起过敏性休克发生率虽然较低,但也可以引起死亡的严重后果,应引起医务工作者的高度重视。
Objective To investigate the characteristics and rules of anaphylactic shock induced by fluoroquinolone antibacterial drug Pefloxacin, and to provide a reference for the rational use of pefloxacin in clinical practice. Methods: To retrieve the case reports of pefloxacin-induced anaphylactic shock through the relevant national medical database and download the original case data by hand statistical analysis. Results Pefloxacin caused 17 cases of anaphylactic shock, 15 cases caused by intravenous injection, 2 cases caused by oral administration; 2 of them died. Conclusion Pefloxacin caused a low incidence of anaphylactic shock, but it can also cause serious consequences of death, which should be paid more attention to by medical workers.