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对32例胸水中找到癌细胞并由影像学及病理学证实为肺癌的患者,用卡铂与白细胞介素2联合胸腔注入治疗癌性胸水;另以26例作对照。治疗组显效12例(37.5%),有效19例(59.4%),无效1例(3.1%),总有效率96.8%。对照组显效7例(26.9%),有效12例(46.5%),无效5例(19.2%),总有效率65.5%。两组疗效有明显差异(P<0.05)。卡铂与白细胞介素2联合治疗癌性胸水,对于病人的行为状态的改善、胸水的消失率、癌性细胞阴转率等具有较好的疗效。如配合放疗或化疗将明显延长病人的生存期。卡铂与白细胞介素2的副作用较小,为肺癌胸水的治疗提供了一种新的有效方法。
In 32 cases of pleural effusion to find cancer cells and confirmed by imaging and pathology of lung cancer patients with carboplatin and interleukin 2 combined with pleural injection of pleural effusion; the other 26 cases as a control. The treatment group was effective in 12 cases (37.5%), effective in 19 cases (59.4%), ineffective in 1 case (3.1%), the total effective rate was 96.8%. The control group was markedly effective in 7 cases (26.9%), effective in 12 cases (46.5%), ineffective in 5 cases (19.2%), the total effective rate was 65.5%. There was significant difference between the two groups (P <0.05). Carboplatin and interleukin 2 combined treatment of cancerous pleural effusion, for the improvement of the patient’s behavioral status, the disappearance rate of pleural effusion, cancer cell negative conversion rate has a good effect. Such as with radiotherapy or chemotherapy will significantly prolong the survival of patients. The small side effects of carboplatin and interleukin 2, for the treatment of pleural effusion of lung cancer provides a new and effective method.