目的:优化赭朴九味润燥汤中桃仁、大黄等的超声波提取工艺。方法:以蒽醌衍生物总含量、脂肪油含量为筛选指标,采用L9(43)正交试验考察提取条件,优选出最佳提取工艺。结果:最佳提取条件为:依次用7,5和5倍体积的60%乙醇提取3次,每次20min;总蒽醌衍生物和脂肪油提取率分别为81.4%和51.2%;浓缩转移率分别为88.7%(n=3,RSD=1.5%)和87.4%(n=3,RSD=5.7%);固形物总收率9.7%(n=3,RSD=8.0%)。结论:本法确定的最佳工艺可为该处方的生产提供依据。 OBJECTIVE: To optimize the ultrasonic extraction process of peach, rhubarb and other peach seeds in Ocher Park. Methods: The total content of anthraquinone derivatives, fatty oil content as a screening index, L9 (43) orthogonal test to investigate the extraction conditions, the best extraction process. Results: The optimal extraction conditions were as follows: the extraction was carried out three times with 60% ethanol in series of 7, 5 and 5 times for 20min each time; the extraction rates of total anthraquinone derivatives and fatty oils were 81.4% and 51.2% respectively; Were 88.7% (n = 3, RSD = 1.5%) and 87.4% (n = 3, RSD = 5.7%) respectively. The total solid yield was 9.7% (n = 3, RSD = 8.0%). Conclusion: The best process identified by this Act may provide the basis for the production of this prescription.