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Madias的研究表明,12导联QRS波振幅之和(∑QRS)与体重的变化呈负相关:28例患者的平均体重从67.6kg增加到86.9kg时,∑QRS从120.2±41.6mV下降到54.8±26.9mV(p=0.0005)。体重与体表心电图关系的进一步研究发现,体重与胸导联V1￣V6导联的∑QRS相关性差,而与肢导、尤其是I和Ⅱ导联QRS波振幅明显相关。根据Kirchff’s第二电压理论:aVR=(I+Ⅱ)×1/2(右图),故单凭aVR导联QRS波振幅的变化则可监测患者体液潴留的动态改变。心衰患者心衰加
Madias’s study showed that the sum of 12-lead QRS amplitudes (ΣQRS) was inversely correlated with changes in body weight: mean body mass of 28 patients increased from 67.6 kg to 86.9 kg, and ΣQRS decreased from 120.2 ± 41.6 mV to 54.8 ± 26.9 mV (p = 0.0005). A further study on the relationship between body weight and body surface ECG found that the body weight was negatively correlated with ΣQRS in lead V1 ~ V6, and significantly correlated with the amplitude of QRS in lead, especially lead I and Ⅱ. According to Kirchff’s second voltage theory: aVR = (I + II) × 1/2 (right), dynamic changes in fluid retention in patients can be monitored solely on changes in amplitude of the aSR QRS. Heart failure patients with heart failure plus