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本文通过动物实验比较研究了附子的乙醇浸膏(Ⅰ)、水溶部分(Ⅱ)和除钙水溶部分(Ⅲ)的强心作用和毒性,结果表明,其强心成分为水溶性的,钙离子在炮制附子的强心作用中起了一定作用。附子虽经炮制,仍存在有毒成分——乌头碱类生物碱,(Ⅰ)的毒性明显大于(Ⅱ)和(Ⅲ)。
In this paper, the cardiac effects and toxicities of the ethanol extract (I), water soluble fraction (II) and calcium-soluble fraction (III) of Aconite were comparatively studied by animal experiments. The results showed that the cardiac components were water-soluble and calcium ions. In the concocted aconite heart function played a certain role. Although concocted with aconite, aconitine alkaloids still exist, and the toxicity of (I) is significantly greater than that of (II) and (III).