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常规水溶液法合成了含钴的锑钨酸盐Na10[Sb2W20Co2O70(H2O)6].34H2O(1).单晶X-射线衍射表明,化合物1含2个三缺位的[SbW9]半单元,2个半单元通过2个WO3簇和2个CoO2簇相连.2个WO3簇和2个CoO2簇形成了1个四金属夹心带,2个WO3簇位于夹心带的中间,2个CoO2簇位于夹心带的两边,该结构为典型的Krebs型结构.体外抗肿瘤活性实验结果表明,化合物1对2种人体肿瘤细胞系—卵巢癌细胞(SK-OV-3)和肝癌细胞(SMMC-7721)—有明显的抑制活性.
Conventional aqueous solution synthesis of cobalt antimony tungstate Na10 [Sb2W20Co2O70 (H2O) 6] .34H2O (1). Single crystal X-ray diffraction showed that Compound 1 contains two three vacancy [SbW9] One half-cell is connected by two WO3 clusters and two CoO2 clusters. Two WO3 clusters and two CoO2 clusters form a four-metal sandwich zone with two WO3 clusters in the middle of the sandwich zone and two CoO2 clusters in the center zone The results of in vitro antitumor activity showed that compound 1 had significant antitumor activity against two human tumor cell lines, ovarian cancer cells (SK-OV-3) and hepatocellular carcinoma cells (SMMC-7721) Significant inhibitory activity.