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目的:对高同型半胱氨酸水平与冠心病的相关性进行调查分析。方法:选择本院2013年9月-2015年9月58例冠心病患者,将其作为观察组,同时选择同期58例健康人群,将其作为对照组,比较两组观察对象同型半胱氨酸水平,同时调查不同心功能评级患者的同型半胱氨酸水平。结果:观察组患者的同型半胱氨酸水平为(17.87±5.42)mmol/L,对照组为(9.24±3.04)mmol/L,组间比较,差异具有统计学意义(P<0.05)。心功能评级为Ⅳ级的患者同型半胱氨酸水平明显高于心功能评级为Ⅱ级、Ⅲ级的患者,差异具有统计学意义(P<0.05)。观察组患者三酰甘油(TG)水平、总胆固醇(TC)水平明显高于对照组,低密度脂蛋白-胆固醇(LDL-C)水平明显低于对照组,组间比较,差异具有统计学意义(P<0.05)。结论:冠心病患者同型半胱氨酸水平明显增高,且患者心功能损害越严重,同型半胱氨酸水平越高。
Objective: To investigate the correlation between homocysteine level and coronary heart disease. Methods: 58 patients with coronary heart disease in our hospital from September 2013 to September 2015 were selected as the observation group and 58 healthy people in the same period were selected as the control group. The levels of homocysteine Levels, and homocysteine levels were also investigated in patients with different cardiac function ratings. Results: The level of homocysteine in the observation group was (17.87 ± 5.42) mmol / L and that in the control group was (9.24 ± 3.04) mmol / L, the difference was statistically significant (P <0.05). Homocysteine levels were significantly higher in patients with grade IV heart function than in patients with grade 2 and grade 3 cardiac function scores (P <0.05). The level of triglyceride (TG), total cholesterol (TC) in the observation group was significantly higher than that in the control group, the level of LDL-C was significantly lower than that of the control group, the difference was statistically significant (P <0.05). Conclusion: Homocysteine levels were significantly elevated in patients with coronary heart disease, and the more severe the cardiac dysfunction was, the higher the homocysteine level was.