氟胞嘧啶是一种选择性抗深部真菌药物,口服和静脉滴注均能达到较高的生物利用度,并能透过血脑屏障。本品治疗念珠菌病和隐球菌病效果确切,副作用小。本文就其药理和临床应用方面的进展作一概述。 Flucytosine is a selective anti-deep fungal drug, oral and intravenous infusion can achieve high bioavailability, and through the blood-brain barrier. This product is effective in treating candidiasis and cryptococcosis with small side effects. This article gives an overview of its progress in pharmacology and clinical applications.