左炔诺孕酮宫内节育系统对预防子宫内膜息肉复发的效果分析

来源 :中国药物经济学 | 被引量 : 0次 | 上传用户:y1271
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目的探讨左炔诺孕酮宫内节育系统对预防子宫内膜息肉复发的效果。方法选取2015年12月至2016年12月沈阳市第六人民医院收治的行手术切除治疗的子宫内膜息肉患者124例,按照1:1比例随机将其分为两组,观察组患者术后放置左炔诺孕酮宫内节育系统,对照组患者不放置,比较两组患者治疗后复发情况、子宫内膜厚度、月经模式以及不良反应发生情况。结果相较于对照组,观察组患者复发率明显降低,差异有统计学意义(P<0.05);治疗后,两组患者子宫内膜厚度较治疗前均有所减少,且观察组明显低于对照组,差异有统计学意义(P<0.05);治疗后,两组患者月经时间和月经量较治疗前均有所改善,且观察组改善明显优于对照组,差异均有统计学意义(均P<0.05)。结论子宫内膜息肉患者术后应用左炔诺孕酮宫内节育系统可有效预防复发,降低子宫内膜增生程度,并能改善患者月经持续时间长和月经量。 Objective To investigate the efficacy of levonorgestrel-induced intrauterine system in preventing the recurrence of endometrial polyps. Methods A total of 124 patients with endometrial polyps underwent surgical resection from December 2015 to December 2016 in Shenyang Sixth People’s Hospital were randomly divided into two groups according to the ratio of 1: Place levonorgestrel intrauterine system, the control group patients were not placed in the treatment group compared the recurrence after treatment, endometrial thickness, menstrual patterns and adverse reactions. Results Compared with the control group, the recurrence rate of observation group was significantly lower, the difference was statistically significant (P <0.05); after treatment, both groups of patients with endometrial thickness than before treatment, and the observation group was significantly lower Control group, the difference was statistically significant (P <0.05); after treatment, the two groups of patients menstrual time and menstrual volume than before treatment were improved, and the observation group improved significantly better than the control group, the differences were statistically significant ( All P <0.05). Conclusion The application of levonorgestrel intrauterine system in postoperative patients with endometrial polyps can effectively prevent recurrence, reduce the degree of endometrial hyperplasia and prolong menstruation duration and menstrual flow.
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