作者选择75例符合下列标准的病人进行了血小板功能和凝血因子的检查:①易发瘀斑为主要主诉;②血小板数正常;③排除自身免疫性血小板减少性紫癜和继发性血小板减少性紫癜;④凝血因子检查正常;⑤最近未服过抗血小板凝聚的药物。根据检查结果,75例病人可分两类,第一类血小板功能正常,第二类血小板功能异常,但两类病人的凝血因子检查均正常。第一类共44例,除1例外,全为女性。年龄17～68岁,平均35岁,瘀斑发作可从幼年开始,亦有到被检前2周才发现。32％自幼发病,27％于1年内发病。31％有家族史。血小板功能检查结果为:束臂试验阳性者24％,出血时间延长者14％,出现巨血小板者60％;43％的病人血小板对ADP(2.2×10~((-6)M),30％的病人对肾上腺素,25％的病人对结缔组织的凝聚性异常,其他病人凝聚性正常;血小板粘滞试验异常者占21％;30％病人出现抗血小板抗体,存在抗血小板抗体的10例病人中,有9例巨血小板的百分比增 The authors selected 75 patients who met the following criteria for platelet function and clotting factor tests: (1) predisposing ecchymoses as primary complaint; (2) normal platelet count; (3) exclusion of autoimmune thrombocytopenic purpura and secondary thrombocytopenic purpura ; Â ’¢ clotting factor test was normal; â’ ¢ not anti-platelet cohesion recently received the drug. According to the test results, 75 patients can be divided into two categories, the first platelet function is normal, the second platelet dysfunction, but both types of patients with clotting factor tests were normal. The first group of 44 cases, with one exception, all women. Aged 17 to 68 years old, with an average of 35 years old, ecchymosis onset can be started from early childhood, but also to be seized 2 weeks before the discovery. 32% from childhood, 27% within 1 year of onset. 31% have a family history. The results of platelet function tests were as follows: 24% positive for arm muscular arm test, 14% prolongation of bleeding time and 60% appearance of giant platelet. In 43% of the patients, platelet count was significantly lower in ADP (2.2 × 10 ~ (-6) M) Of patients to adrenaline, 25% of patients with abnormal connective tissue aggregation, cohesion of other patients with normal; platelet adhesion test abnormalities accounted for 21%; 30% of patients with anti-platelet antibodies, anti-platelet antibodies in 10 patients In 9 cases, the percentage of giant platelets increased