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3.1.5有机溶剂/去污剂处理有机溶剂/去污剂混合物(S/D)破坏包膜病毒的脂膜,一旦破坏脂膜病毒不可能再与感染细胞结合。该法不能灭活非包膜病毒。已应用的典型灭活条件是0.3%磷酸三丁酯(TNBP)和1%非离子去污剂,吐温-80或Triton X-100,在24℃用Triton X-100处理至少4 h,或用吐温-80处理至少6 h。当用TNBP/Triton X-100时,某些制剂在4℃处理获得了成功。高脂含量可能影
3.1.5 Organic Solvent / Detergent Treatment The organic solvent / detergent mixture (S / D) disrupts the lipid membranes of enveloped viruses and can no longer bind to the infected cells once the lipid viruses have been destroyed. The law can not inactivate non-enveloped viruses. Typical inactivation conditions that have been applied are 0.3% tributyl phosphate (TNBP) and 1% non-ionic detergent, Tween-80 or Triton X-100, treated with Triton X-100 at 24 ° C for at least 4 h Or treated with Tween-80 for at least 6 h. Some preparations were successful at 4 ° C when using TNBP / Triton X-100. High fat content may shadow