本文报道5例干燥综合征(SS)并发周期性麻痹,系前者引起继发性肾小管性酸中毒所致。本病起病隐匿,起病症状为乏力、纳差、低热、心悸等非特异性表现,亦可有多饮多尿等症,起病4～12年后方出现反复发作低血钾性四肢轧瘫。本病以劳累、妊娠及感染为诱因,本组除1例同时伴有慢活肝外,余4例均系原发性SS而无其他结缔组织或自身免疫疾 This article reports 5 cases of Sjogren’s syndrome (SS) complicated by periodic paralysis, the former caused by secondary renal tubular acidosis. The disease occult onset, symptoms of onset of fatigue, anorexia, fever, palpitations and other non-specific performance, may also have polyhydramnios embolism, 4 to 12 years after the onset of recurrent hypokalemia limbs paralysis . The disease to fatigue, pregnancy and infection as the incentive, in addition to a group of patients with slow and live in addition to the liver, the other four cases were primary SS without other connective tissue or autoimmune diseases