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目的:观察分析氯解磷定合并阿托品治疗重度有机磷农药中毒的临床效果,总结相关经验,为今后重度有机磷农药中毒患者的治疗提供理论依据。方法:选取我院2009年11月～2012年11月间收入的60例重度有机磷农药中毒的患者作为研究对象。使用解磷定合并阿托品用药的方式对其进行治疗,并观察其治疗效果。结果:60例重度有机磷农药中毒患者中,治愈57例,死亡3例,死亡率5.0%。平均住院天数7.8±1.7天,M样消失时间4.6±4.1h,N样消失时间12.1±2.2h,出现不良反应的患者有8例,不良反应发生率为13.3%。结论:突击量氯解磷定合并阿托品治疗重度有机磷农药中毒的效果较好,治愈率较高,不良反应在可接受的范围之内,可以在临床上应用、推广。
OBJECTIVE: To observe and analyze the clinical effects of chlorophenanthroline combined with atropine in the treatment of severe organophosphorus pesticide poisoning, and to summarize relevant experiences so as to provide a theoretical basis for the treatment of severe organophosphorus pesticide poisoning patients in the future. Methods: Sixty patients with severe organophosphorus pesticide poisoning from November 2009 to November 2012 in our hospital were selected as the research object. The use of phosphate solution combined with atropine medication for its treatment, and observe its therapeutic effect. Results: Among 60 patients with severe organophosphorus pesticide poisoning, 57 cases were cured and 3 died, the mortality rate was 5.0%. The mean duration of hospital stay was 7.8 ± 1.7 days, M ± disappear time was 4.6 ± 4.1h, N disappearance time was 12.1 ± 2.2h. There were 8 cases of adverse reactions and the incidence of adverse reactions was 13.3%. Conclusions: Assault amount of chlorophenanthroline combined with atropine in the treatment of severe organophosphorus pesticide poisoning is better, the cure rate is higher, the adverse reactions within the acceptable range, can be applied in clinic, promotion.