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目的研究降钙素原与C反应蛋白联合检测在脓毒血症发病的早期诊断意义。方法选取2011年8月至2013年8月我院收治的早期脓毒血症患者与同期同年龄段接受健康体检的健康人,各44例,分为研究组和对照组。分别采用双抗夹心免疫荧光发光法和免疫比浊测定法测定两组对象的降钙素原与C反应蛋白水平,并进行比较。结果经检测,研究组患者降钙素原与C反应蛋白水平明显高于对照组,差异有统计学意义(P<0.05)。结论患有脓毒血症患者的降钙素原与C反应蛋白水平明显高于健康人群,临床上可将上述两项指标作为对脓毒血症诊断指标,并对该疾病治疗效果进行评价的客观参考指标。
Objective To study the early diagnosis of sepsis with combined detection of procalcitonin and C-reactive protein. Methods From August 2011 to August 2013, 44 patients with early sepsis admitted to our hospital and 44 healthy subjects of the same age were enrolled into study group and control group. The levels of procalcitonin and C-reactive protein in the two groups were determined by double-antibody sandwich immunofluorescence assay and immunoturbidimetric assay, respectively. Results The levels of procalcitonin and C-reactive protein in the study group were significantly higher than those in the control group (P <0.05). Conclusions The levels of procalcitonin and C-reactive protein in patients with sepsis are significantly higher than those in healthy people. The above two indexes can be clinically used as a diagnostic indicator of sepsis and the therapeutic effect of the disease is evaluated Objective reference index.