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为了研究甲壳寡糖对力竭运动小鼠红细胞免疫粘附功能和抗氧化功能的影响。对4周龄昆明种小鼠随机分为对照组、运动组、甲壳寡糖组。运动组和甲壳寡糖组进行4周的游泳训练,最后一次进行力竭游泳后即刻采用心脏取血,肝素抗凝,测定红细胞免疫粘附功能及红细胞抗氧化功能指标。结果发现:实验4周后,甲壳寡糖组RBC-C3bRR和RBC-SOD活性明显高于运动组(P<0.01),RBC-C3bRR亦高于对照组(P<0.05);而RBC-ICR和RBC-MDA含量明显低于运动组(P<0.01)。表明:小鼠服用甲壳寡糖可提高机体红细胞免疫功能,减轻自由基介导的脂质过氧化反应。
In order to study the effect of chitooligosaccharides on erythrocyte immune adherence function and antioxidant function in exhausted exercise mice. Kunming mice of 4 weeks old were randomly divided into control group, exercise group and chitosan oligosaccharide group. Exercise group and chitooligosaccharides group for 4 weeks of swimming training, the last time after exhaustive swimming with cardiac blood, heparin anticoagulation, erythrocyte immune adhesion function and erythrocyte antioxidant function. The results showed that RBC-C3bRR and RBC-SOD activity in chitooligosaccharides group was significantly higher than that in exercise group (P <0.01) and RBC-C3bRR was also higher than that in control group (P <0.05) RBC-MDA content was significantly lower than exercise group (P <0.01). The results showed that the administration of chitooligosaccharides in mice could improve the immune function of the body and alleviate the free radical-mediated lipid peroxidation.