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目的探讨酮咯酸氨丁三醇联合山莨菪碱治疗肾绞痛的疗效。方法选取2011—2013年沧州市中心医院急诊科收治的肾绞痛患者457例,随机分为治疗组(228例)与对照组(229例)。治疗组患者予以酮咯酸氨丁三醇联合山莨菪碱治疗,对照组患者予以盐酸哌替啶联合山莨菪碱治疗。观察两组患者临床疗效及不良反应(如恶心、呕吐、头晕、尿潴留、低血压、过敏等)发生情况。结果两组患者总有效率比较,差异无统计学意义(P>0.05);治疗组患者不良反应发生率低于对照组,差异有统计学意义(P<0.05)。结论酮咯酸氨丁三醇联合山莨菪碱治疗肾绞痛的疗效显著,且不良反应少,安全性高。
Objective To investigate the curative effect of ketorolac tromethamine combined with anisodamine on renal colic. Methods 457 renal colic patients admitted to Emergency Department of Cangzhou Central Hospital from 2011 to 2013 were randomly divided into treatment group (n = 228) and control group (n = 229). Patients in the treatment group were treated with ketorolac tromethamine combined with anisodamine, and patients in the control group were treated with pethidine hydrochloride and anisodamine. To observe the clinical efficacy and adverse reactions (such as nausea, vomiting, dizziness, urinary retention, hypotension, allergies, etc.) in the two groups. Results There was no significant difference in the total effective rate between the two groups (P> 0.05). The incidence of adverse reactions in the treatment group was lower than that in the control group (P <0.05). Conclusion ketorolac tromethamine combined with anisodamine treatment of renal colic significant effect, and adverse reactions, high safety.