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目的 :探讨前列腺炎栓治疗慢性前列腺炎药理学作用原理。方法 :采用细菌性及非细菌性两种大鼠模型 ,考察该药对前列腺组织炎症反应的影响 ;采用急性血瘀证动物模型 ,观察其活血作用 ;同时进行了一般抗炎、镇痛、体内外抑菌实验。结果与结论 :前列腺炎栓可明显抑制前列腺组织炎症反应 ,恢复前列腺分泌功能 ;具有很好的抗炎、镇痛、抑菌作用 ;对血瘀证大鼠血液流变学改变亦有一定改善
Objective : To explore the pharmacological action principle of prostatitis suppository in the treatment of chronic prostatitis. METHODS: Bacterial and non-bacterial rat models were used to investigate the effect of the drug on the inflammatory response of prostate tissue. The blood-activating effect was observed in animal models of acute blood stasis syndrome; general anti-inflammatory, analgesic, and Internal and external antibacterial experiments. RESULTS AND CONCLUSION: Prostatitis suppository can significantly inhibit the inflammatory reaction of prostate tissue and restore the function of prostate secretion. It has good anti-inflammatory, analgesic and antibacterial effects; it also has some improvement in blood rheology changes in rats with blood stasis syndrome.