对154例EH家族史进行病例对照调查。结果表明,EH组一级亲属高血压患病率(14.6％)约为对照组(2.7％)的5倍。先证者父亲的高血压患病率为男性先证者高于女性先证者,母亲的患病率则与之相反;男性先证者父亲高血压患病率高于其母亲患病率,而女性先证者则反之。高血压遗传力估计为73.5％。表明遗传因素在决定易患性变异上起着重要作用,遗传倾向具有明显的性别差异,与环境因素亦相关。 154 cases of family history of EH case-control survey. The results showed that the prevalence of hypertension in first-degree relatives of EH group (14.6%) was about 5 times that of the control group (2.7%). The proband’s father’s prevalence of hypertension was higher in male probands than in female probands, while the prevalence of mothers was the opposite. The prevalence of father’s hypertension in male probands was higher than that of their mothers, Female probands on the contrary. Heritability of high blood pressure is estimated at 73.5%. Genetic factors play an important role in determining the variation of susceptibility, genetic predisposition has obvious gender differences, and environmental factors are also related.