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夹竹桃科Adenium obesum在非洲东部作为箭毒或治疗淋病。这种植物的提取物具有细胞毒性,曾从该植物中分离出几种强心苷与黄酮醇。最近从这种植物的叶中分离到4种孕烷(1～4),并且证明C-16/C-17位的不饱和状态对这些孕烷衍生物的细胞毒活性
Apocynaceae Adenium obesum in eastern Africa acts as a poison for archery or cure gonorrhea. The plant extract is cytotoxic and several cardiac glycosides and flavonols have been isolated from the plant. Four types of pregnane (1-4) have recently been isolated from the leaves of this plant and demonstrate the cytotoxic activity of the unsaturated state of C-16/C-17 on these pregnane derivatives.