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痢特灵(呋喃唑酮Furazolidonum)是肠道、泌尿系统感染的常用药,亦用于溃疡病。临床报道对6-磷酸葡萄糖脱氢酶(下简称G-6-PD)缺乏患者引起急性溶血性反应,但严重黄疸少见。现报告痢特灵引致严重黄疸1例。王某男,43岁,兴宁县人。因眼黄、尿黄、恶心和疲乏2日于1980年9月19日来诊。患十二指肠溃疡病多年,近因右上腹痛反复发作。服痢特灵首次0.2g/次,每天3次,同服维生素B族等药物,服后第4天尿色深黄、疲乏,继则眼黄、恶心、口苦、疲惫乏力。既往无黄疸及肝炎史,童年曾患过蚕豆病,但此后进食蚕豆未见不适反应。检查:神智清楚、合
Furazolidonum (furazolidone Furazolidonum) is commonly used drugs for intestinal and urinary tract infections, also used for ulcer disease. Clinical reports on the 6-phosphoglucose dehydrogenase (G-6-PD) lack of patients caused acute hemolytic reaction, but rare jaundice. A case of severe jaundice caused by furazolidone has been reported. Wang male, 43 years old, Xingning County. On the 2nd due to eye yellow, dark urine, nausea and fatigue on September 19, 1980 visit. Suffering from duodenal ulcer disease for many years, due to recurrent right upper quadrant pain. Furazolidone for the first time 0.2g / time, 3 times a day, with the service vitamin B and other drugs, the first 4 days after serving dark yellow urine, tired, then the eye yellow, nausea, mouth bitter, tired fatigue. No previous history of jaundice and hepatitis, childhood had had fava bean disease, but after eating no symptoms of broad bean reaction. Check: Clear mind, together