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二、方案B 1.诱导期——4周(见图5) 诱导前一天晚上的准备同方案A(方案B、C中与方案A中相似的说明均从略)。CTX:1200mg/m~2,Ⅳ.15—30分钟推完,第0天用药后继续补液使尿比重<1.010,至少维持24小时。为防止呕吐,主张先给静脉DX 10mg/m~2和口服氯丙嗪15mg/m~2。Pred:60mg/m~2/天分3次口服,第1—28天。VCR:1.5mg/m~2,≤2mg/次,Ⅳ.1次/周×4,第1、8、15、22天。
II. Protocol B 1. Induction period - 4 weeks (see Figure 5) Induction of the preparation of the night before is the same as that of Scheme A (the explanations similar to those in Scheme A and C are omitted). CTX: 1200mg / m ~ 2, IV.15-30 minutes push finished, 0 days after the continued use of fluid rehydration to make urinary specific gravity <1.010, at least for 24 hours. In order to prevent vomiting, advocate giving intravenous DX 10mg / m ~ 2 and oral chlorpromazine 15mg / m ~ 2. Pred: 60mg / m ~ 2 / day 3 times orally, the first 1-28 days. VCR: 1.5mg / m ~ 2, ≤ 2mg / time, Ⅳ.1 times / week × 4, the first 1,8,15,22 days.