巴比妥盐、肝素、皮质激素、低温以及过度换气等,均能减轻大脑缺氧性损害的后遗症。但在大多数临床病例中,效果是不满意的,或者某些药物的用量需超出正常使用的范围。本研究通过动物实验,试图探讨苯妥英钠对大脑停滞性缺氧(Cerebral stagnanthypoxia)是否具有保护作用。为此目的,将家兔产生脑缺氧一段时间后,分三组以生理盐水、硫喷妥钠及苯妥英钠进行治疗,并对阻断脑血流引起的继发性病理改变进行比较。 Barbiturates salt, heparin, corticosteroids, hypothermia and hyperventilation, can reduce the consequences of hypoxic brain damage. However, in most clinical cases, the effect is unsatisfactory, or some drugs need to be used beyond the scope of normal use. In this study, animal experiments were conducted to explore whether phenytoin has protective effect on cerebral stagnant hypoxia. For this purpose, rabbits were subjected to hypoxia for a period of time and then treated with saline, sodium thiopental and phenytoin sodium in three groups and compared with the secondary pathological changes that blocked the cerebral blood flow.