论文部分内容阅读
确诊多发性骨髓瘤(MM)后,应按Durie和Salmon标准进行临床分期,以制定治疗措施。对无症状及病情稳定的Ⅰ期患者可暂不治疗,密切观察,每2个月进行1次免疫球蛋白、尿常规、血常规及骨髓象检查。如出现M蛋白增高、贫血加重,骨痛和骨髓浸润明显时,即行治疗。可望延缓发生耐药性,减少发生急性白血病的机会。Ⅱ、Ⅲ期患者应在强力支持治疗下给予较强烈的化疗。
After diagnosis of multiple myeloma (MM), clinical staging should be performed according to the criteria of Durie and Salmon to develop therapeutic measures. Asymptomatic and stable patients with stage Ⅰ can be temporarily treated, close observation, immunoglobulin, urine routine, blood and bone marrow biopsy every 2 months. Such as the emergence of M protein increased anemia, bone pain and bone marrow infiltration significantly, that line treatment. It is expected to delay the occurrence of drug resistance and reduce the chance of developing acute leukemia. Ⅱ, Ⅲ patients should be given strong supportive treatment of more intense chemotherapy.