西方国家的酒精性肝病近年有所增加,80～90%的肝硬化为酒精性肝硬化。在美国纽约州,酒精性肝病为25～44岁男性第2位最常见的死亡原因,因此应重视过量饮酒对人体的危害性。酒精的代谢酒精80～90%由肝脏代谢,酒精主要经过肝细胞胞液的乙醇脱氢酶催化,氧化为乙醛,乙醛再经乙醛脱氢酶催化成乙酸,最后形成二氧化碳。酒精在以上氧化过程中脱下大量的氢,辅酶Ⅰ被还原为还原型辅酶Ⅰ,使还原型辅酶 Western alcoholic liver disease in recent years has increased, 80 to 90% of cirrhosis of alcoholic cirrhosis. In New York, USA, alcoholic liver disease is the second most common cause of death among men aged 25-44 years. Therefore, it is important to pay attention to the dangers of excessive alcohol consumption on the human body. Alcohol metabolism 80-90% alcohol metabolism by the liver, alcohol mainly through the liver cell cytosol alcohol dehydrogenase, oxidation of acetaldehyde, acetaldehyde by acetaldehyde dehydrogenase into acetic acid, and finally the formation of carbon dioxide. Alcohol in the above oxidation process take off a lot of hydrogen, coenzyme Ⅰ is reduced to reduced coenzyme Ⅰ, the reduced coenzyme