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[目的]了解巴中市部分健康人群HBV感染情况,探讨健康人群乙肝预防的对策与措施。[方法]对1456名健康体检人群,采用酶联免疫吸附法(ELISA)测定HBsAg、抗-HBs、HBeAg、抗-HBe、抗-HBc,按年龄、性别分组进行5项标志物的分析比较。[结果]HBsAg总阳性率为7.28%(男、女分别为7.90%、5.97%);性别分布差异无统计学意义(P﹥0.05),年龄分布差异有统计学意义(P﹤0.05)。5项指标总体上性别分布差异无统计学意义(P﹥0.05),而在年龄上差异有统计学意义(P﹤0.01)。[结论]人群中HBV感染率高,免疫水平低,易感者多。建议制订青少年强化和成人乙肝疫苗扩大免疫计划,减少乙肝发病率。
[Objective] To understand the status of HBV infection in some healthy people in Bazhong and explore the countermeasures and measures for prevention of hepatitis B in healthy people. [Methods] A total of 1456 healthy volunteers were enrolled in this study. The levels of HBsAg, anti-HBs, HBeAg, anti-HBe and anti-HBc were measured by enzyme-linked immunosorbent assay (ELISA) [Results] The overall positive rate of HBsAg was 7.28% (male and female were 7.90% and 5.97% respectively). There was no significant difference in gender distribution between the two groups (P> 0.05). The distribution of age was statistically significant (P <0.05). There was no significant difference in gender distribution among the five indicators (P> 0.05), but there was a significant difference in age (P <0.01). [Conclusion] The population of HBV infection rate is high, immune level is low, more susceptible. Proposed to develop adolescent and adult hepatitis B vaccine to expand immunization programs to reduce the incidence of hepatitis B.