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正电子CT(电子计算X线断层扫描)的特点为利用碳(~(11)C)、氮(~(13)N),氧(~(15)O)等构成机体主要元素的同位素,获得总量的图象。这一新技术已在心血管领域中得到应用。本文对此作一简介。局部心肌代谢的研究利用碳(~(11)C)和氮(~(13)N)研究局部心肌能量代谢是正电子CT的主要研究范围。通常采用~(11)C棕桐酸盐与糖类似物质-~(18)F~-2-氟2脱氧葡萄糖(~(18)FDG)研究心肌的能量代谢。心肌利用脂肪酸,糖,乳酸等作为能量的来源。禁食时,食后及缺血状态下,其利用率各异,与仅以糖为能量来源的脑不同,总的代谢情况较为复杂。 1.脂肪的代谢: Go1dstein等在兔的左心房内注入~(11)C
Positron emission tomography (CT) is characterized by the use of isotopes of carbon (~ (11) C), nitrogen (~ (13) N) and oxygen The total amount of images. This new technology has been applied in the cardiovascular field. This article gives an introduction. Study on local myocardial metabolism Using carbon (~ (11) C) and nitrogen (~ (13) N) to study local myocardial energy metabolism is the main research area of positron emission tomography. The energy metabolism of myocardium is usually studied by ~ (11) C palmitate and its analogue of ~ (18) F ~ -2-fluorodeoxyglucose (~ (18) FDG) Myocardial use of fatty acids, sugar, lactate, etc. as a source of energy. Fasting, postprandial and ischemic conditions, the utilization of different, and only the sugar as the energy source of different brain, the overall metabolic situation is more complicated. 1. Fat Metabolism: Go1dstein et al injected ~ (11) C into the left atrium of rabbits