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目的:分析某“三甲”医院2011年—2013年间3种Ⅰ类切口手术(甲状腺手术、乳腺手术、疝气修补术)围术期患者预防用抗菌药物整治前后的相关因素,供合理用药参考。方法:采用回顾性方法,对某“三甲”医院2011年—2013年间3种Ⅰ类切口手术患者489例,分析抗菌药物专项整治活动后抗菌药物使用时间、药品种类等指标,评价抗菌药物使用合理性。结果:经干预后3种Ⅰ类切口围手术期患者预防用药物的选择、用药时机、术后用药时间、联合用药等因素较专项整治活动前均明显得到改善;抗菌药物专项整治后的预防使用率由干预前的41.94%降至2.63%,经比较其差异有统计学意义(P<0.05)。结论:3种Ⅰ类切口围手术期患者预防用抗菌药物经专项整治,提高了围术期患者抗菌药物的合理用药水平,但仍存在较不规范现象,亟待采取相关措施加以干预。
OBJECTIVE: To analyze the related factors before and after prophylaxis with antibacterials in patients undergoing perioperative management of one type Ⅰ incision (thyroid surgery, breast surgery, hernia repair) in 2011-2013 at a “Three-A” hospital for reference of rational drug use . Methods: A retrospective analysis was conducted on 489 patients with type Ⅰ incision surgery in one of the “Three-A” hospitals from 2011 to 2013. Anti-bacterial drug use time and type of drugs were analyzed after the special anti-bacterial drug treatment activities to evaluate the efficacy of antibacterial drugs Use rationality. Results: After intervention, the preventive medication selection, the timing of medication, the time of medication, the combination of drugs and other factors in the perioperative period of three kinds of incision perioperative patients were significantly improved compared with that before the special rectification activities. The prophylactic use of antimicrobial agents The rate decreased from 41.94% before intervention to 2.63%, which was statistically significant (P <0.05). CONCLUSIONS: Three kinds of perioperative patients with type Ⅰ perioperative prophylaxis of antimicrobial agents have been specially treated to improve the rational use of antimicrobial drugs in perioperative patients. However, there are still some non-standard phenomena, and it is urgent to take relevant measures to intervene.