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研究了树舌多糖 GF 对 HePA 小鼠~3H-leu 血清蛋白掺入量的影响。结果表明:树舌多糖 GF 能明显降低 HePA 小鼠血清蛋白~3H—leu 的掺入量,与肿瘤对照组比较 P<0.05。同时进一步用 PAGE 分析血清蛋白组分发现,荷瘤对照组与正常组比较,在 MW 约12KD 处增加一组分,而用药后该组分消失;在 MW 约13KD 和5KD 处,给药组与荷瘤对照组比较蛋白含量降低,与正常组相近。
The effect of GFPS on the incorporation of 3H-leu serum protein in HePA mice was studied. The results showed that the content of 3H-leu in serum of HePA mice was significantly decreased by the polysaccharide of ganoderma patency GF, and P<0.05 compared with the tumor control group. At the same time, further analysis of serum protein components by PAGE revealed that the tumor-bearing control group increased one component at a MW of about 12KD compared with the normal group, and disappeared after the drug was administered; at a MW of about 13KD and 5KD, the drug administration group In the tumor-bearing control group, the protein content was decreased, similar to the normal group.