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作者研究了对氨苯砜敏感和耐药的麻风杆菌在鼠足垫中的生长曲线,以判断其传染性。敏感菌来自未治瘤型麻风病人的皮下结节。耐药菌来自氨苯砜治疗超过5年、早期疗效良好而后来病情恶化的瘤型麻风。皮下结节按Shepard氏法(1960)加以处理,取菌悬液0.03毫升(内含麻风杆菌7500条)注射于CBA小鼠右后足垫,然后置于装以空气调节器的房间内饲养。6个月后每月按Shepard和McRca氏
The authors studied the growth curve of lepirudin sensitive and resistant to dapsone in mouse foot pads to determine its infectivity. Sensitive bacteria from untreated leprosy patients with subcutaneous nodules. Drug-resistant bacteria from dapsone treatment for more than 5 years, the early effect of a good condition and later the deterioration of the tumor-type leprosy. Subcutaneous nodules were treated according to the Shepard’s method (1960). 0.03 ml of bacterial suspension (7500 leprosy contained) was injected into the right rear foot pad of CBA mice and then housed in a room equipped with an air conditioner. Shepard and McRca’s are monthly for six months