一般认为在非授乳期发生乳汁分泌是异常现象,因其多伴有闭径,故又称为泌乳闭径综合征,早在1850年代就已有人报告冠以首次报告者名字的有以下三个综合征。1.Chiari-frommel 综合征Chiari(1855)首次报告了分娩后长期有泌乳,闭经及子宫卵巢萎缩2例,其后 frommel(1852)报告了同样病症1例, It is generally believed that milk secretion in non-lactating period is an anomaly, because it is often associated with closed-loop, it is also known as lactation-closure syndrome, as early as the 1850s have been reported as the first name of the reporter has the following three Syndrome. Chiari-frommel syndrome Chiari (1855) first reported 2 cases of long-term lactation, amenorrhea and uterine ovary atrophy after childbirth, followed bymel (1852) reported the same disease in 1 case,