采用CODPL、CAT、HDMTX、EA、VPDL连续强烈化疗方案治疗小儿急性淋巴细胞白血病（ALL）33例，全部病例获得骨髓缓解，93.9％获完全缓解（CR），2例在诱导期死于败血症。缓解病例随访1年以上，1年、2年、3年CR率分别为93.5％、85.7％、833％，4例患儿分别在缓解后9个月、11个月、16个月、25个月复发。认为早期连续强烈化疗方案治疗儿童ALL奏效快、CR率高、CR期长，最严重的并发症仍是骨髓抑制导致严重感染。 Thirty-three cases of children with acute lymphoblastic leukemia (ALL) were treated with CODPL, CAT, HDMTX, EA, and VPDL. All cases received bone marrow remission, 93.9% achieved complete remission (CR), and 2 cases died of sepsis at the induction period. The remission cases were followed up for more than one year. The 1-year, 2-year, and 3-year CR rates were 93.5%, 85.7%, and 833%, respectively. Four patients had 9 months, 11 months, 16 months, and 25 months after remission. Monthly recurrence. It is believed that early continuous strong chemotherapy regimens are effective in treating children’s ALL with a high CR rate and a long CR period. The most serious complication is still severe myelosuppression.