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目的:观察帕米膦酸二钠联合同期化疗治疗乳腺癌骨转移的疗效。方法:将我院近期收治的乳腺癌骨转移患者80例随机分为治疗组和对照组各40例,治疗组采用帕米膦酸二钠联合同期化疗治疗,对照组单纯使用同期化疗治疗。结果:治疗组与对照组在疼痛缓解方面、生活质量方面以及骨质修复方面比较,治疗组明显优于对照组,差异具有统计学意义(P<0.05)。结论:帕米膦酸二钠联合同期化疗治疗乳腺癌骨转移的疗效显著,值得推荐。
Objective: To observe the curative effect of pamidronate disodium combined with concurrent chemotherapy on bone metastasis of breast cancer. Methods: Eighty patients with breast cancer with bone metastasis admitted in our hospital were randomly divided into treatment group (40 cases) and control group (40 cases). The treatment group received pamidronate disodium combined with concurrent chemotherapy and the control group received concurrent chemotherapy alone. Results: The treatment group and the control group were significantly better than the control group in pain relief, quality of life and bone repair, the difference was statistically significant (P <0.05). Conclusion: Pamidronate disodium combined with concurrent chemotherapy for the treatment of breast cancer with bone metastasis of significant effect, it is recommended.