患者女性，63岁，因左面部上下眼睑肿胀伴低热10天入院。体检：左上下眼睑、左颧上部明显红肿有压痛，中央有小片黑色坏死，用抗生素治疗无效，红肿、坏死性黑痂扩大至直径6cm，皮损组织涂片真菌检查发现大量分隔菌丝，培养为须癣毛癣菌，诊断皮肤深部真菌感染，服伊曲康唑0.2，每日2次，52天基本痊愈。 Patient female, 63 years old, with upper eyelid swelling left lower extremity with fever 10 days admitted. Physical examination: the left upper and lower eyelids, left obvious upper left cheek swelling and tenderness, the central small pieces of black necrosis, treatment with antibiotics ineffective, swelling, necrosis black crusts expanded to 6cm in diameter, lesions of tissue smear found a large number of fungal separation mycelium, culture Trichophyton mentagrophytes for the diagnosis of skin deep fungal infection, service itraconazole 0.2, 2 times a day, 52 days basically cured.