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目的分析2009—2014年1 018例梅毒流行病特征,为临床预防医学和疾病控制提供合理依据。方法收集2009年1月—2014年12月收治的梅毒患者1 018例。所有患者用凝集法(TPPA)筛查,阳性者进一步用胶体金再确认,两种方法阳性者再做TRUST检查。结果 2009—2014年梅毒发病数量呈现逐年上升,每年男性发病数分别为29、58、74、89、93、112例,女性分别为45、75、95、87、125、136例,总数分别为74、133、169、176、218和248例。18~40岁、60岁以上老年人是高发年龄段。共报告梅毒1 018例,男性455例,女性563例。年平均患病率为0.42%,由2009年的0.37%上升至2014年的0.45%,6年来总体呈逐年增长,2012年略有下降,随后又呈现缓慢上升趋势。隐性梅毒占41.75%,Ⅱ期梅毒占38.70%,Ⅰ期梅毒占15.42%,胎传梅毒占2.36%,Ⅲ期梅毒占1.77%。结论近6年梅毒发病数量逐年上升,应加大重点人群干预检测力度,以控制梅毒的传播,降低梅毒的发病率。
Objective To analyze the epidemiological characteristics of 1 018 cases of syphilis in 2009-2014 and provide a reasonable basis for clinical preventive medicine and disease control. Methods A total of 1 018 cases of syphilis were collected from January 2009 to December 2014. All patients were screened by agglutination (TPPA). Positives were further retested with colloidal gold. TRUST was performed again in both methods. Results The incidence of syphilis increased year by year from 2009 to 2014. The annual incidence of syphilis was 29,58,74,89,93,112 and the number of women was 45,75,95,87,125,136 respectively 74, 133, 169, 176, 218 and 248 cases. 18 ~ 40 years old, 60 years of age or older is a high incidence of age. A total of 1 018 cases of syphilis were reported, 455 were male and 563 were female. The annual average prevalence was 0.42%, rising from 0.37% in 2009 to 0.45% in 2014, showing a year-on-year increase in 6 years and a slight decrease in 2012, followed by a slow upward trend. Recessive syphilis accounted for 41.75%, Ⅱ syphilis accounted for 38.70%, Ⅰ syphilis 15.42%, fetal syphilis accounted for 2.36%, Ⅲ syphilis accounted for 1.77%. Conclusions The incidence of syphilis has been increasing year by year in recent 6 years. Intensive intervention testing should be stepped up to control the spread of syphilis and reduce the incidence of syphilis.