羧甲基纤维素钠(CMC-Na),在制剂上的应用日趋广泛,现作一概述。一、用作助悬剂: CMC-Na水溶液具粘性,能增加分散媒的粘度,并能被吸附在药物微粒周围,形成机械的保护性薄膜,维持混悬微粒的均匀分散。CMC一Na胶液属于膺塑性(即假塑性)流体,其胶液分子间结构可阻止混悬微粒的沉降和结块。制品沉降容积较大.具有触 Carboxymethyl cellulose sodium (CMC-Na), in the preparation of the increasingly widespread use, now an overview. First, as a suspending agent: CMC-Na aqueous solution with viscosity, can increase the viscosity of the dispersion medium, and can be adsorbed on the drug particles around the formation of mechanical protective film to maintain the uniform dispersion of suspended particles. CMC-Na glue belongs to the plastic (ie, pseudoplastic) fluid, and its glue intermolecular structure can prevent the suspended particles from settling and agglomeration. Product sedimentation volume larger. With a touch