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目的评价血清糖化白蛋白与2型糖尿病患者血脂的相关性。方法比较409例2型糖尿病患者与91例对照组间空腹血糖(FSG)、糖化血红蛋白(HbA1c)及糖化白蛋白(GA)的差异。结果病例组与对照组间FSG、HbA1c及GA均有统计学差异。根据HbA1c水平将病例组分为4组,FSG在2组与3组间差异无统计学意义(P=0.24);4组TG中,2组和1组、3组、4组间差异无统计学意义(P=0.216,P=0.058,P=0.8);CHO在1组和2组间,3组和4组间差异无统计学意义(P=0.233,P=0.609);其余各组间四项指标差异均有统计学意义(P<0.01)。统计结果也显示GA与HbA1c相关性良好(r=0.867)。结论 GA与血脂水平密切相关,并适用于短期血糖水平监测。
Objective To evaluate the correlation between serum glycated albumin and blood lipids in type 2 diabetic patients. Methods The difference of fasting blood glucose (FSG), glycosylated hemoglobin (HbA1c) and glycated albumin (GA) between 409 type 2 diabetic patients and 91 control subjects was compared. Results There were significant differences in FSG, HbA1c and GA between case group and control group. According to the level of HbA1c, the cases were divided into four groups. There was no significant difference in FSG between two groups and three groups (P = 0.24). There was no significant difference between the two groups in TG, two groups, three groups and four groups (P = 0.216, P = 0.058, P = 0.8). There were no significant differences in CHO between groups 1 and 2, between groups 3 and 4 (P = 0.233, P = 0.609) The differences of the four indicators were statistically significant (P <0.01). The statistical results also showed a good correlation between GA and HbA1c (r = 0.867). Conclusion GA is closely related to blood lipid levels and is suitable for short-term monitoring of blood glucose levels.