Monitoring regional cerebral oxygen saturation throughout the perioperative clinical process is important for successful patient outcomes.Cerebral oximeters based on near-infrared spectroscopy(NIRS)have already been used for monitoring brain oxygenation and hemodynamics to avoid intraoperative ischemic stroke and reduce postoperative cognitive dysfunction.The current devices are all designed to be used as a bedside monitor,limiting their use to situations that center around a hospital bed.There is a current lack of wearable,miniaturized,wireless equipment that can extend brain oxygenation monitoring to motion tasks or tight spaces.We design a head-mounted wearable wireless oxygen saturation monitoring on head(WORTH)band based on NIRS for monitoring regional cerebral oxygen saturation.The band is embedded with a highly integrated central block,which comprises an optical module,a microprocessor unit,a wireless communication module,and a power management module.The performance of the WORTH band is evaluated by a controlled hypoxia experiment and a squat-to-stand experiment.The results confirm that the WORTH band can record cerebral oxygen saturation with an accuracy comparable to that of a clinical monitor and demonstrate that it is also effective during motion tasks.