苯并噁嗪酮及其衍生物具有重要的医用价值及生理活性,因此合成该类骨架结构受到很多化学家的重视.报道了一种以含N,O-双齿导向基团的苯氧乙酸为底物,通过钯催化的C—H键活化反应一步构建C—N键的新方法,合成了一系列苯并噁嗪类化合物.该方法反应条件温和,操作简便,合成效率高. Benzoxazinone and its derivatives have important medical value and physiological activity, so the synthesis of such framework has attracted the attention of many chemists.A kind of N, O-bidentate-oriented phenoxyacetic acid As a substrate, a series of benzoxazin compounds were synthesized by palladium-catalyzed C-H bond activation reaction in one step and a series of benzoxazin compounds were synthesized.The reaction conditions are mild, easy to operate and high in synthesis efficiency.